Endeavor
Endeavour
That's not a big difference is it -- a small spelling error.
Unless it is on this sign:

From
Local6:
Shuttle's Name Misspelled On NASA Launch Pad Sign
Someone Called Kennedy Space Center NASA To Fix Typo
The first NASA sign at launch pad 39A encouraging the next launch of space shuttle Endeavour at Kennedy Space Center was misspelled and noticed by someone looking at the craft.
When the shuttle rolled out from the Vehicle Assembly Building Wednesday, a giant "Go Endeavour" sign was put on a fence in front of the craft.
However, one item was missing from the sign: the "u" in Endeavour.
Someone spotted the mistake and called KSC to fix it, WKMG-TV reported.
NASA scrambled someone out to pad 39A with a new sign that has orbiter Endeavour's name spelled correctly.
Oopsie...
Both are technically correct, but they had it right the first time. As an American project, like behavior/behaviour, we should use, 'endeavor.'
Endeavour is used in the UK/Canadian spellings.