Out of the frying pan and into the fire

There has been a justifiable push to remove BPA from food-grade plastics. It makes for a much better plastic but it has serious long-term health problems. The industry has substituted BPS and BPFfor the last couple of years but...

From the US National Institutes of Health, Environmental Health Perspectives:

Bisphenol S and F: A Systematic Review and Comparison of the Hormonal Activity of Bisphenol A Substitutes
We identified the body of literature to date, consisting of 32 studies (25 in vitro only, and 7 in vivo. The majority of these studies examined the hormonal activities of BPS and BPF and found their potency to be in the same order of magnitude and of similar action as BPA (estrogenic, antiestrogenic, androgenic, and antiandrogenic) in vitro and in vivo. BPS also has potencies similar to that of estradiol in membrane-mediated pathways, which are important for cellular actions such as proliferation, differentiation, and death. BPS and BPF also showed other effects in vitro and in vivo, such as altered organ weights, reproductive end points, and enzyme expression.

In plain english, from Science Daily:

Exposure to common chemicals in plastics linked to childhood obesity
Bisphenol S (BPS) and bisphenol F (BPF) are manufactured chemicals used in certain kinds of plastic, in the lining of aluminum-canned food and drinks, and in thermal paper from cash-register receipts. These chemicals have been used as a replacement for bisphenol A (BPA), a well-known endocrine-disrupting chemical that harms human health by interfering with the body's hormones.

"This research is significant because exposure to these chemicals is very common in the United States. BPS and BPF use is growing because manufacturers are replacing BPA with these chemicals, so that is contributing to the frequency of exposure," said the study's corresponding author, Melanie Jacobson, Ph.D., M.P.H, of NYU School of Medicine in New York, N.Y. "Although diet and exercise are still understood to the main drivers of obesity, this research suggests that common chemical exposures may also play a role, specifically among children."

Who allowed this substitution to be done? Doesn't seem like there was much testing done...